Zoledronate, also known as zoledronic acid, is classified as a bisphosphonate and, more broadly, an antiresorptive medication. Zoledronate is approved by the US Food and Drug Administration (FDA) for various indications, including the prevention and treatment of osteoporosis in males and postmenopausal females, glucocorticoid-induced osteoporosis, Paget disease of bone, hypercalcemia of malignancy, multiple myeloma, and solid tumor bone metastases. Zoledronate is administered intravenously and is commonly prescribed and indicated to treat various metabolic bone disorders, including both malignant and benign diseases. As zoledronate is administered intravenously, it can be utilized in patients with an intolerance or contraindication to oral bisphosphonates.This activity comprehensively reviews indications, mechanisms of action, pharmacokinetics, adverse drug reactions, monitoring strategies, drug-drug interactions, and clinical toxicology of zoledronate, highlighting the crucial roles of healthcare professionals in the comprehensive management of zoledronate therapy. This activity provides clinicians with the necessary expertise and tools for safe and proficient Zoledronate administration by elucidating distinct roles and facilitating collaborative practices within the interprofessional healthcare team. With this comprehensive knowledge regarding zoledronate, clinicians can elevate patient outcomes and establish elevated standards of care when prescribing the drug effectively to patients with bone disorders and other related conditions.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/148094
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABOS - 1.0 Point; Credit Type(s): Accredited CME (ABOS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABOHNS - 1.0 Point; Credit Type(s): Self-Assessment (ABOHNS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adult Reconstruction, All Practice Areas (e.g. ethics), Complex General Surgical Oncology, Endocrinology, Diabetes, and Metabolism, General Orthopaedics, General Otolaryngology, General Pediatrics, Geriatric Medicine, Hematology, Hospital Medicine, Internal Medicine, Medical Oncology, Medical Toxicology, Nephrology, Orthopaedic Sports Medicine, Orthopaedic Trauma, Pediatric Endocrinology, Pediatric Hematology-Oncology, Pediatric Nephrology, Pediatric Rheumatology, Rheumatology, Shoulder and Elbow, Sports Medicine, Surgery of the Hand, Surgery of the Spine