Trimethylaminuria (TMAU) is a rare metabolic disorder resulting in the accumulation of trimethylamine. Primary TMAU is an autosomal recessive genetic condition that results in the deficiency or dysfunction of the hepatic enzyme flavin monooxygenase 3. Trimethylamine is a foul-smelling metabolite excreted in body fluids causing affected individuals to exude a fishy odor. While not a life-threatening condition in and of itself, TMAU can have significant psychological and social implications. Proper diagnosis and implementation of appropriate management strategies can help improve symptoms and overall quality of life for patients with TMAU. This activity reviews the pathogenesis, pathophysiologic mechanisms, clinical features, diagnostic testing, and management strategies of TMAU and highlights the integral role of the interprofessional team in treating patients with this rare condition.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/146119
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Chemical Pathology, Endocrinology, Diabetes, and Metabolism, Gastroenterology, General Pediatrics, General Surgery, Hospital Medicine, Internal Medicine, Molecular Genetic Pathology, Pediatric Endocrinology, Pediatric Gastroenterology