Valproate Toxicity

Valproate Toxicity

Valproate toxicity results from an excessive accumulation of valproic acid in the body, often triggered by factors like high dosages, rapid dose adjustments, or interactions with other medications. Symptoms vary widely, including gastrointestinal distress symptoms such as nausea and vomiting, neurological manifestations like drowsiness, confusion, and, in severe cases, coma or fatality. Timely identification of risk factors and early symptom recognition is pivotal for intervening and mitigating adverse consequences. Treatment strategies involve a multifaceted approach, including supportive care to manage symptoms and specific interventions like L-carnitine therapy or hemodialysis to remove excess valproic acid from the bloodstream.Through this course, participants better understand valproate toxicity comprehensively, including proficient identification of risk factors, thorough patient assessment techniques, and implementing appropriate diagnostic and therapeutic measures. Additionally, collaborating with an interprofessional team is emphasized, as this enhances patient outcomes significantly by facilitating seamless communication and coordination across various healthcare disciplines. By leveraging the expertise and resources of diverse specialists, patient care is optimized, ensuring timely and targeted interventions that improve safety and clinical effectiveness.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/30391
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: IPCE Credits: 1.5 hours
    AMA PRA Category 1 Credit™️: 1.5 hours
    Nursing: 1.5 hours
    Pharmacy: 1.5 hours
  • MOC Credit Details: ABS - 1.5 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.5 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABA - 1.5 Point; Credit Type(s): Lifelong Learning (ABA)
    ABIM - 1.5 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.5 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.5 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Chemical Pathology, Critical Care Medicine, Forensic Pathology, General Pediatrics, General Surgery, Hospital Medicine, Internal Medicine, Medical Toxicology, Neurocritical Care, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Neurology
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