Polyglandular Autoimmune Syndrome Type I

Polyglandular Autoimmune Syndrome Type I

Autoimmune polyglandular syndrome type 1 (APS-1), also known as autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), is characterized by the triad of hypoparathyroidism, Addison disease, and chronic mucocutaneous candidiasis. APS-1 is due to mutations in the autoimmune regulatory gene (AIRE); so far about 60 different mutations have been described. This is a potentially underdiagnosed condition due to the rarity and enormous variability in its presentation. Besides the above triad, a host of other autoimmune diseases may present with APS-1. This activity describes the pathophysiology, presentation, and diagnosis of autoimmune polyglandular syndrome type 1 and highlights the role of the interprofessional team in its management.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/27408
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
    Nursing: 1.0 hours
    Pharmacy: 1.0 hours
  • MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
    ABOHNS - 1.0 Point; Credit Type(s): Self-Assessment (ABOHNS)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Chemical Pathology, Endocrinology, Diabetes, and Metabolism, General Otolaryngology, General Pediatrics, General Surgery, Infectious Disease, Internal Medicine, Molecular Genetic Pathology, Pediatric Endocrinology, Pediatric Gastroenterology, Pediatric Infectious Diseases, Pediatric Rheumatology, Rheumatology
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