Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)

Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)

Colorectal cancer remains one of the deadliest cancers in the United States and is more prevalent in persons aged younger than 50.[27] Most colorectal cancers are sporadic, but inherited syndromes cause 5% to 10%  of cases. The most common heritable colorectal cancer is Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC). Identifying patients with Lynch syndrome is important because these patients have up to an 80% lifetime risk of colorectal cancer, a 60% lifetime risk of endometrial cancer, and, depending on the variant, an increased risk for other primary cancers, including gastric, ovarian, small bowel, urothelial (ureter, renal pelvis, and bladder), prostate, biliary tract, pancreatic, brain (glioblastoma), cutaneous.This activity provides a framework for understanding the etiology of Lynch syndrome, including how to diagnose patients effectively, differentiate somatic from inheritable causes, and when to monitor based on molecular presentation. The interprofessional team is equipped to utilize recent guidelines to reduce the risk of malignancy, leading to a better prognosis for patients with HNPCC.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/24608
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
    Nursing: 1.0 hours
    Pharmacy: 1.0 hours
  • MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABTS - 1.0 Point; Credit Type(s): Accredited CME (ABTS)
    ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
    ABTS - 1.0 Point; Credit Type(s): Self-Assessment (ABTS)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Adolescent Medicine, Complex General Surgical Oncology, Gastroenterology, General Pediatrics, General Surgery, GI (incl. Liver, Pancreas, Bilary), Internal Medicine, Medical Oncology, Molecular Genetic Pathology, Non-Thoracic Surgery, Pediatric Gastroenterology, Pediatric Hematology-Oncology
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