Folinic acid, also known as 5-formyl tetrahydrofolic acid or leucovorin, treats various cancers when employed with 5-fluorouracil (5-FU). Additionally, leucovorin serves as an antidote to folic acid antagonists like methotrexate. Folinic acid’s properties allow it to function as an antidote, chemotherapy-modulating agent, and rescue agent for the chemotherapy category of medications. This activity will discuss the approved indications, intricate mechanism of action, and contraindications for folinic acid while addressing its role in treating specific cancer types and megaloblastic anemia. The activity will also discuss the adverse event profile, off-label applications, and monitoring protocols associated with folinic acid, offering insights for the interprofessional team involved in the care of patients undergoing treatment with 5-FU, methotrexate, and other conditions where folinic acid proves indispensable.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/21866
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Chemical Pathology, Gastroenterology, General Pediatrics, General Surgery, Hematology, Infectious Disease, Internal Medicine, Medical Oncology, Pediatric Gastroenterology, Pediatric Hematology-Oncology, Pediatric Infectious Diseases, Pediatric Rheumatology, Rheumatology