Fexofenadine, a second-generation antihistamine, is a metabolite of terfenadine. The US Food and Drug Administration (FDA) approved fexofenadine to treat seasonal allergic rhinitis and chronic idiopathic urticaria. Fexofenadine is approved for use in both children and adults. Children may be eligible for treatment starting at 6 months or older, depending on the specific indications.Fexofenadine acts by selectively antagonizing H1 receptors on cell surfaces across various organ systems, thereby affecting inflammatory mediators. As a second-generation antihistamine, fexofenadine exhibits reduced affinity for cholinergic and α-adrenergic receptors, which results in minimal anticholinergic effects. This drug also demonstrates high specificity for H1 receptors and lacks anticholinergic activity. This activity provides information about fexofenadine, including its indications, mechanism of action, administration, adverse event profile, contraindications, and other critical factors such as monitoring, drug interactions, and clinical toxicology. This activity also aims to enhance the competence of interprofessional healthcare providers involved in treating patients with allergic rhinitis and chronic urticaria by providing them with the necessary skills to improve patient care.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/21720
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABOHNS - 1.0 Point; Credit Type(s): Self-Assessment (ABOHNS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Allergy, Chemical Pathology, General Otolaryngology, General Pediatrics, General Surgery, Hospital Medicine, Internal Medicine, Pediatric Emergency Medicine, Rhinology