Cholinergic Crisis

Cholinergic Crisis

A cholinergic crisis develops as a result of overstimulation of nicotinic and muscarinic receptors at the neuromuscular junctions. This is usually secondary to the inactivation or inhibition of acetylcholinesterase (AChE), the enzyme responsible for the degradation of acetylcholine (ACh). Excessive accumulation of acetylcholine (ACh) at the neuromuscular junctions and synapses causes symptoms of both muscarinic and nicotinic toxicity. These include cramps, increased salivation, lacrimation, muscular weakness, paralysis, muscular fasciculation, diarrhea, and blurry vision. This activity examines the presentation and evaluation of a patient undergoing a cholinergic crisis and the role of the health professional team in coordinating the care of this acute condition.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/19471
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.5 hours
    Nursing: 1.5 hours
    Pharmacy: 1.5 hours
  • MOC Credit Details: ABS - 1.5 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.5 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABA - 1.5 Point; Credit Type(s): Lifelong Learning (ABA)
    ABTS - 1.5 Point; Credit Type(s): Accredited CME (ABTS)
    ABIM - 1.5 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.5 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.5 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
    ABTS - 1.5 Point; Credit Type(s): Self-Assessment (ABTS)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Adolescent Medicine, Ambulatory/Outpatient, Bariatric Surgery, Cardiac Anesthesia, Chemical Pathology, Complex General Surgical Oncology, Critical Care, Critical Care Medicine, Forensic Pathology, Gastroenterology, General Operative Anesthesia, General Pediatrics, General Surgery, Hospital Medicine, Internal Medicine, Medical Toxicology, Neuro Anesthesia, Neurocritical Care, Pediatric Anesthesia, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Gastroenterology, Pediatric Neurology, Pediatric Pulmonology, Pediatric Surgery, Pulmonary Disease, Rheumatology, Surgical Critical Care, Thoracic Anesthesia, Vascular Surgery
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