In this online, self-learning activity: Alagille syndrome (ALGS) is a rare, autosomal dominant Notch-signaling-dysfunction genetic disorder, first described in 1969 by Daniel Alagille. Its estimated prevalence is approximately 1 in 30,000, and it is caused by mutations in one of two genes, JAG1 or NOTCH2, which play a crucial role in the development and function of several organs. Most children diagnosed with ALGS will need a liver transplant before reaching adulthood, with a transplant-free survival rate of 24-41% by adulthood. The condition is characterized by hepatic, cardiac, vascular, skeletal, renal, and ocular abnormalities, along with distinct facial features. There is also a substantial economic burden associated with the condition, driven primarily by frequent outpatient and costly inpatient visits. And rare diseases like ALGS can pose psychological and physical challenges for patients and families, often with inadequate support and resources.
- Provider:ScientiaCME
- Activity Link: https://www.scientiacme.org/cme-542-111-0-1-99-alagille-syndrome-cme
- Start Date: 2024-12-26 06:00:00
- End Date: 2024-12-26 06:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
- MOC Credit Details: ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: Source: Ipsen - Amount: 24950.0 - Is Kind Support: False
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: No, it's free
- Measured Outcome: Learner Competence, Learner Knowledge, Learner Performance
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Gastroenterology, General Pediatrics, Internal Medicine, Pediatric Gastroenterology, Pediatric Transplant Hepatology, Transplant Hepatology
Warning: file_put_contents(/nas/content/live/sleepliteracy/wp-content/uploads/wpdiscuz/cache/comments/.htaccess): Failed to open stream: Permission denied in /nas/content/live/sleepliteracy/wp-content/plugins/wpdiscuz/utils/class.WpdiscuzCache.php on line 161