Abaloparatide, a synthetic peptide analog of parathyroid hormone-related protein (PTHrP), is used to manage and treat osteoporosis. Osteoporosis is characterized by reduced bone mineral density due to changes in bone microstructure, resulting in an elevated risk of fractures. The US Food and Drug Administration (FDA) has approved abaloparatide use in postmenopausal women at high risk of fracture due to osteoporosis. In addition, abaloparatide is frequently prescribed for individuals who exhibit intolerance to or have not responded to conventional osteoporosis treatments.In a double-blind, controlled, randomized phase II clinical trial, the safety and efficacy of abaloparatide demonstrated superiority in enhancing overall bone mineral density compared to teriparatide and placebo within these treatment groups. As osteoporosis primarily affects postmenopausal women, it is crucial to provide clinicians with essential knowledge about abaloparatide, which is vital to ensure optimal patient care and prevent disease progression. This activity reviews the indications, mechanism of action, administration, pharmacokinetics, and associated warnings related to abaloparatide. By enhancing the expertise of healthcare professionals with evidence-based strategies, this activity seeks to empower clinicians to incorporate abaloparatide into clinical practice seamlessly. This contribution aims to improve patient outcomes in the management of osteoporosis.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/148092
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABOS - 1.0 Point; Credit Type(s): Accredited CME (ABOS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: All Practice Areas (e.g. ethics), Foot and Ankle, General Orthopaedics, General Surgery, Geriatric Medicine, Internal Medicine, Orthopaedic Sports Medicine, Orthopaedic Trauma, Pediatric Orthopaedic Surgery, Rheumatology, Surgery of the Hand, Surgery of the Spine