Alagille Syndrome

Alagille Syndrome

Alagille syndrome (ALGS) is a multisystem autosomal dominant disorder with a wide variety of clinical manifestations. It is also known as arteriohepatic dysplasia, Alagille-Watson syndrome, Watson-Miller syndrome, or syndromic bile duct paucity. The clinical manifestations are variable, even within the same family, and commonly include hepatic (cholestasis, characterized by bile duct paucity on liver biopsy), cardiac (primarily involving the pulmonary arteries), skeletal (butterfly vertebrae), ophthalmologic (posterior embryotoxon), and facial abnormalities. Alagille syndrome can range from a subclinical presentation to a life-threatening condition, with a mortality rate of up to 10%. This activity reviews the evaluation and treatment of Alagille syndrome and highlights the role of the interprofessional team in evaluating and treating patients with this condition.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/17321
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
    Nursing: 1.0 hours
    Pharmacy: 1.0 hours
  • MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABTS - 1.0 Point; Credit Type(s): Accredited CME (ABTS)
    ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
    ABTS - 1.0 Point; Credit Type(s): Self-Assessment (ABTS)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Adolescent Medicine, Cardiovascular, Cardiovascular Disease, Clinical Pathology, Congenital Cardiac, Gastroenterology, General Pediatrics, General Surgery, GI (incl. Liver, Pancreas, Bilary), Internal Medicine, Molecular Genetic Pathology, Nephrology, Neuropathology (incl. Neuromuscular), Pediatric Cardiology, Pediatric Nephrology, Pediatric Rheumatology, Renal/Medical Renal, Rheumatology, Soft Tissue & Bone
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