Alpha-1 antitrypsin (AAT) deficiency is a genetically inherited condition characterized by the impaired production of the alpha-1 antitrypsin protein. This protein protects the body from neutrophil elastase, an enzyme released during inflammation and infection. Due to defective production, individuals with AAT deficiency experience reduced levels of functional AAT in the blood and lungs, leading to the destruction of alveoli and resulting in conditions such as emphysema and bronchiectasis. Additionally, abnormal AAT levels can cause protein accumulation in the liver, leading to liver damage. Symptoms often appear between the ages of 20 and 50, and cigarette smoking can exacerbate lung function decline in affected individuals.The activity provides participants with comprehensive knowledge of the evaluation and management of AAT deficiency, including its etiology, clinical manifestations, and diagnostic approaches. By understanding the disease’s complexity, participants learn to identify and differentiate AAT deficiency from other conditions, screen at-risk populations, and implement effective treatment strategies. Collaboration with an interprofessional team—including pulmonologists, hepatologists, and genetic counselors—enhances patient care by ensuring a multidisciplinary approach when diagnosing and managing AAT deficiency.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/31484
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: IPCE Credits: 1.0 hours
AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABTS - 1.0 Point; Credit Type(s): Accredited CME (ABTS)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABTS - 1.0 Point; Credit Type(s): Self-Assessment (ABTS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Ambulatory/Outpatient, Clinical Pathology, Critical Care Medicine, Cytopathology, Gastroenterology, General Operative Anesthesia, General Pediatrics, General Surgery, General Thoracic, GI (incl. Liver, Pancreas, Bilary), Hospital Medicine, Internal Medicine, Molecular Genetic Pathology, Pediatric Critical Care Medicine, Pediatric Gastroenterology, Pediatric Pulmonology, Pediatric Transplant Hepatology, Pulmonary Disease, Pulmonary, Mediastinum, Surgical Critical Care, Transplant Hepatology