Argininemia is an autosomal recessive disorder causing hyperammonemia secondary to arginine accumulation. It is a disorder first noticed in children with growth reduction, slowing cognition, and milestone development. Often diagnosed at birth through newborn screening (NBS), affected newborns are found to have elevated levels (up to 4 times) of arginine. Its management is similar to other classic urea cycle disorders, although with mild or absent hyperammonemia. If hyperammonemia is present, it responds adequately to ammonia-reducing interventions. Chronic treatment consists of protein restriction along with nitrogen-scavenging medications. This activity describes the evaluation and management of argininemia and explains the role of the interprofessional team in improving care for patients with this condition.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/17811
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Chemical Pathology, Critical Care Medicine, Developmental-Behavioral Pediatrics, Endocrinology, Diabetes, and Metabolism, Gastroenterology, General Pediatrics, GI (incl. Liver, Pancreas, Bilary), Hospital Medicine, Internal Medicine, Molecular Genetic Pathology, Neonatal-Perinatal Medicine, Neurocritical Care, Neurodevelopmental Disabilities, Pediatric Anesthesia, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Gastroenterology, Pediatric Transplant Hepatology, Transplant Hepatology