Canagliflozin is an oral C-glycosyl compound antihyperglycemic agent. Sodium-glucose co-transporter 2 (SGLT2) is expressed on the proximal renal tubules and is primarily responsible for the reabsorption of 90% of the glucose filtered by our kidneys. Canagliflozin inhibits the proximal renal tubules’ SGLT2 receptors. This action decreases renal glucose absorption and the renal threshold for glucose and increases urinary excretion. Canagliflozin was approved in 2013 by the Food and Drug Administration (FDA). Canagliflozin is utilized to treat patients who are diagnosed with type 2 diabetes mellitus (T2DM) and other disease states with either approved or non-FDA-approved indications. This activity focuses on the indications, contraindications, mechanism of action, adverse effects, and other critical features of canagliflozin. Incorporating considerations for special populations, such as pregnancy, lactation, and renal or hepatic impairment, strengthens the implementation of safe prescribing practices. This comprehensive educational activity aims to promote proficiency in utilizing this knowledge to maximize medication efficacy and minimize the risk of adverse drug events.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/159958
- Start Date: 2024-12-01 06:00:00
- End Date: 2024-12-01 06:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Advanced Heart Failure and Transplant Cardiology, All Practice Areas (e.g. ethics), Ambulatory/Outpatient, Cardiovascular Disease, Critical Care Medicine, Endocrinology, Diabetes, and Metabolism, Gastroenterology, General Operative Anesthesia, General Surgery, Geriatric Medicine, Hospital Medicine, Internal Medicine, Nephrology, Neurocritical Care