In this online, self-learning activity: Cholestatic liver diseases are characterized by a disruption of bile flow in the biliary tree. They include a range of biliary diseases that affect the biliary epithelium, resulting in cholestasis, inflammation, fibrosis, and cirrhosis, and they account for about 14% of liver transplants in the US. One of the most common progressive cholangiopathies that primarily affects adults is primary biliary cholangitis (PBC). Formerly known as primary biliary cirrhosis, PBC involves the progressive fibrosis of the small intrahepatic bile ductules, and its prevalence ranges between 1.91 to 40.2 per 100,000. The pathogenesis of each has not been well-defined but is thought to involve environmental triggers leading to an immune hyper-response and inflammation in those who are genetically susceptible. The complications of PSC also include colon and hepatobiliary cancer, and the median predicted survival for patients with PBC is six to 16 years with rates differing between asymptomatic patients and symptomatic patients (16 vs. 7.5 years, respectively). Those diagnosed with the disease also experience decreased productivity and lower quality of life (QOL).
- Provider:ScientiaCME
- Activity Link: https://www.scientiacme.org/cme-530-111-0-1-99-cholangiopathy-primary-biliary-sclerosing-cholangitis-pbc-psc-cme
- Start Date: 2024-07-19 05:00:00
- End Date: 2024-07-19 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
- MOC Credit Details: ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
- Commercial Support: Source: Ipsen - Amount: 24950.0 - Is Kind Support: False
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: No, it's free
- Measured Outcome: Learner Competence, Learner Knowledge, Learner Performance
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Gastroenterology, Internal Medicine