Crigler-Najjar Syndrome

Crigler-Najjar Syndrome

Crigler-Najjar syndrome is a congenital autosomal recessive inherited disorder that leads to nonhemolytic jaundice. This syndrome is caused by an absence (CN1) or profoundly decreased level (CN2) of the enzyme UDP-glucuronosyltransferase due to a genetic defect in the UGT1A1 gene. This condition results in hyperbilirubinemia that may present soon after birth. Severe forms of this disease can cause hyperbilirubinemia, which can potentially cause irreversible brain damage. Hence, prompt diagnosis and treatment are of utmost importance. This activity reviews the evaluation and management of Crigler-Najjar syndrome. This activity also highlights the interprofessional team’s role in caring for newborns with this condition.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/20123
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: IPCE Credits: 1.0 hours
    AMA PRA Category 1 Credit™️: 1.0 hours
    Nursing: 1.0 hours
    Pharmacy: 1.0 hours
  • MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
    ABOHNS - 1.0 Point; Credit Type(s): Self-Assessment (ABOHNS)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Gastroenterology, General Otolaryngology, General Pediatrics, General Surgery, GI (incl. Liver, Pancreas, Bilary), Hospital Medicine, Internal Medicine, Molecular Genetic Pathology, Neonatal-Perinatal Medicine, Neurodevelopmental Disabilities, Neurotology, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Gastroenterology, Pediatric Neurology, Pediatric Otolaryngology
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