Dermatofibrosarcoma protuberans (DFSP) stands as a rare soft tissue sarcoma that emerges in the dermis and is often found on the trunk and proximal extremities. This condition can present as a slowly developing, robust plaque, exhibiting shades of pink or violet, underscoring the challenge of timely diagnosis. The chromosomal translocation t(17;22)(q22;q13) leads to the formation of the abnormal fusion protein COL1A1-PDGFB, contributing to its pathogenesis. Surgical excision, whether through Mohs micrographic surgery or wide local excision, remains the cornerstone of treatment. However, the potential for local recurrence necessitates vigilant monitoring posttreatment, with radiation therapy sometimes employed to mitigate this risk. Emerging treatments such as tyrosine kinase inhibitors show promise in managing advanced or metastatic disease, highlighting the evolving landscape of DFSP management.Healthcare professionals engaging in this comprehensive course on DFSP gain invaluable insights into its pathophysiology, clinical presentation, evaluation, and management. Through a deeper understanding of DFSP’s molecular underpinnings and clinical behavior, clinicians enhance their diagnostic acumen, facilitating earlier recognition and biopsy. Moreover, the course equips learners with proficiency in employing various treatment modalities, including surgical techniques like Mohs micrographic surgery and wide local excision. Also explored is the importance of collaboration with an interprofessional team, as this amplifies the effectiveness of patient care because diverse expertise contributes to informed decision-making and comprehensive treatment planning. By integrating multidisciplinary approaches, healthcare providers optimize patient outcomes by minimizing the risk of local recurrence and addressing advanced or metastatic disease more effectively.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/20385
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Complex General Surgical Oncology, Dermatopathology, General Pediatrics, Internal Medicine, Medical Oncology, Molecular Genetic Pathology, Soft Tissue & Bone