Dupilumab is an injectable prescription medication administered subcutaneously to treat severe and refractory forms of atopic dermatitis. The US Food and Drug Administration (FDA) approved the medication in April 2017 to treat moderate-to-severe, resistant, atopic dermatitis unresponsive to conventional therapy, including topical corticosteroids. Dupilumab is also used as a maintenance treatment for asthma and chronic rhinosinusitis with nasal polyposis in adults and children, in conjunction with other medications.Dupilumab is also now FDA-approved for prurigo nodularis and eosinophilic esophagitis. Non-FDA-approved indications include allergic contact dermatitis, hand dermatitis, chronic spontaneous urticaria, and alopecia areata. Extensive literature suggests the efficacy of dupilumab in treating conditions characterized by Th2-mediated inflammation. Clinical trials are currently in the pipeline to explore the potential of dupilumab in treating autoimmune blistering diseases, such as bullous pemphigoid. This activity describes dupilumab, including its mechanism of action, adverse event and safety profiles, eligible patient populations, and contraindications. It also highlights the interprofessional team’s role in managing patients on dupilumab treatment.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/144777
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABOHNS - 1.0 Point; Credit Type(s): Self-Assessment (ABOHNS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Chemical Pathology, General Otolaryngology, General Pediatrics, General Surgery, Hospital Medicine, Internal Medicine, Rhinology