PROGRAM DESCRIPTION: Eosinophilic esophagitis (EoE) is a chronic immune mediated disease of the esophagus that is increasingly recognized as a cause of dysphagia in children and adults. Over the past 3 decades, EoE has transformed from a little-known condition to a well-characterized, chronic, clinicopathologic disease often encountered in clinical practice by otolaryngologists in patients presenting for evaluation of dysphagia. EoE is characterized clinically by symptoms related to esophageal dysfunction and histologically by eosinophil-predominant inflammation. It significantly affects patients’ quality of life and, if left untreated, can result in fibrotic complications. This session will provide a comprehensive review of the pathophysiology of EoE, starting from major pathogenic mechanisms (genetics, type 2 inflammation, epithelial barrier dysfunction, gastroesophageal reflux, allergens, infections and microbiota), diagnostic criteria including endoscopic findings and biopsy requirements, and treatment including elimination diets, proton pump inhibitors (PPIs), topical steroids, and most recently biologics. The aim of treatment is to improve clinical symptoms while obtaining mucosal healing and avoiding long-term complications. Diagnostic guidelines and evidence-based management recommendations will be reviewed. Despite advances over the past 30 years, important knowledge gaps about EoE remain and future therapeutic targets will be discussed as well.OUTCOME OBJECTIVE 1: Consider eosinophilic esophagitis (EoE) in the differential diagnosis of patients presenting with a chief complaint of dysphagiaOUTCOME OBJECTIVE 2: Initiate an appropriate evaluation for eosinophilic esophagitis (EoE) based on history, endoscopy, and biopsyOUTCOME OBJECTIVE 3: Discuss current available treatment strategies for eosinophilic esophagitis (EoE) including diet modification, medical therapies, and biologic agentsBACKGROUND STATEMENT: EoE is an atopic condition of the esophagus which has been increasingly recognized in patients over the past 30 years. Otolaryngologists need to be aware of this condition in patients presenting with the chief complaint of dysphagia and have some understanding of diagnosis and management.
- Provider:American Academy of Otolaryngology – Head & Neck Surgery Foundation
- Activity Link: http://media.mycrowdwisdom.com.s3.amazonaws.com/aao-hnsf/2023_Annual_Meeting_Webcasts/23AMW2409551.mp4
- Start Date: 2023-10-01 05:00:00
- End Date: 2023-10-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
- MOC Credit Details: ABOHNS - 1.0 Point; Credit Type(s): Self-Assessment (ABOHNS)
- Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Yes
- Measured Outcome: Community/Population Health, Learner Competence, Learner Knowledge, Learner Performance, Patient Health
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Laryngology