Factor V deficiency is a rare bleeding disorder that can be inherited or acquired. Factor V is a vital component of the coagulation cascade, a glycoprotein synthesized primarily in the liver and released in the bloodstream in an inactive form. Blood vessel injury activates blood clotting factors, including factor V. Activated factor V ultimately accelerates fibrinogen conversion to fibrin, the protein meshwork that reinforces the clot. Factor V deficiency disrupts this intricate clotting mechanism, impairing the body’s ability to form stable blood clots efficiently. Symptoms can range from mild mucosal bleeding to severe, life-threatening hemorrhage. Diagnosis usually requires a coagulation profile and blood tests to measure the level and activity of various coagulation components, including factor V. Genetic testing may also be performed in people with the inherited form to identify the specific genetic mutation responsible for the disorder and guide family planning decisions. Treatment typically involves managing and preventing bleeding episodes through various strategies, including clotting factor replacement therapy using agents like fresh frozen plasma. Immunosuppression may be necessary in patients with the acquired disease type. This activity for healthcare professionals is designed to enhance learners’ competence in evaluating and managing factor V deficiency. Participants gain a better grasp of the condition’s pathophysiology, presentations, and evidence-based diagnostic and treatment strategies. Learners become prepared to collaborate with an interprofessional team caring for individuals with factor V deficiency.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/139939
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Ambulatory/Outpatient, General Operative Anesthesia, General Pediatrics, General Surgery, Hematology, Internal Medicine, Molecular Genetic Pathology, Pediatric Hematology-Oncology