Fatal Familial Insomnia

Fatal Familial Insomnia

Fatal familial insomnia is a very rare and invariably fatal autosomal dominant neurodegenerative prion disease caused by a mutation of the prion protein (PRNP) gene. Hallmarks of the disease include aggressively progressive insomnia; subsequent autonomic disturbances, including tachycardia, hyperhidrosis, and hypertension; cognitive disturbances, including deficits in short-term memory and attention; balance problems; and endocrine dysfunction. The disease is currently incurable and has an average duration of 18 months, ultimately leading to death. A detailed history and neurological examination are of paramount importance as fatal familial insomnia is primarily a clinical diagnosis. Treatment is centered mainly on symptomatic relief and palliative care, as there is no cure for FFI. This activity for healthcare professionals aims to enhance learners’ competence in selecting appropriate diagnostic tests, managing fatal familial insomnia, and fostering effective interprofessional teamwork to improve outcomes.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/21637
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.5 hours
    Nursing: 1.5 hours
    Pharmacy: 1.5 hours
  • MOC Credit Details: ABS - 1.5 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.5 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABA - 1.5 Point; Credit Type(s): Lifelong Learning (ABA)
    ABIM - 1.5 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.5 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.5 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: General Pediatrics, General Surgery, Internal Medicine, Molecular Genetic Pathology, Neuropathology (incl. Neuromuscular), Pediatric Neurology, Sleep Medicine
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