Felty syndrome is a rare extra-articular manifestation of seropositive rheumatoid arthritis characterized by RA, neutropenia, and splenomegaly. While the etiology remains somewhat obscure, baseline data suggests an association with certain human leukocyte antigen (HLA) subtypes. The development of antibodies to granulocyte colony-stimulating factor (G-CSF) heralds the onset of neutropenia. Other autoantibodies may be evident. T-cell entities may also demonstrate this anomaly. Severe or recurrent infection is particularly concerning due to neutropenia, especially in the skin and respiratory system. Therapy is directed towards improving the white blood cell count and avoiding infections. This is performed, in large part, with steroids, methotrexate, and monoclonal antibody therapy. This activity focuses on increasing awareness about this rare condition and discussing the importance of interprofessional care in treating affected patients.Clinicians gain a deep understanding of the therapeutic landscape for Felty syndrome, focusing on treatment strategies and enhancing their ability to link dermatological presentations to systemic conditions. By fostering increased awareness, this activity aims to equip healthcare professionals with the knowledge and skills needed to diagnose and manage individuals with Felty syndrome effectively while optimizing patient outcomes.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/21671
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Gastroenterology, General Surgery, GI (incl. Liver, Pancreas, Bilary), Hematology, Hematopathology (LN, Spleen), Hospital Medicine, Internal Medicine, Molecular Genetic Pathology, Rheumatology, Soft Tissue & Bone