Flucytosine, an antimetabolite within the antifungal drug class, addresses systemic and severe candida and cryptococcus infections. Operating exclusively within fungal cells, this medication spares mammalian cells, enhancing its safety profile. Flucytosine is often used with another antifungal agent; its solo application is discouraged due to the inherent risk of developing fungal resistance. Clinical oversight is crucial, given the drug’s substantial reliance on renal function. Vigilant monitoring is paramount, with diligent dosing adjustments warranted in cases of renal compromise to mitigate potential toxicity risks.This activity discusses flucytosine’s indications, mechanism of action, and contraindications, providing insights for healthcare professionals caring for patients grappling with severe fungal infections, particularly those caused by candida and cryptococcus. The course accentuates critical facets, encompassing the drug’s adverse event profile and other pivotal considerations pertinent to healthcare team members managing patients afflicted with these challenging infections.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/21829
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABTS - 1.0 Point; Credit Type(s): Accredited CME (ABTS)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABTS - 1.0 Point; Credit Type(s): Self-Assessment (ABTS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adult Cardiac, Cardiothoracic, Cardiovascular, Chemical Pathology, Critical Care, Critical Care Medicine, General Pediatrics, General Surgery, General Thoracic, Hospital Medicine, Infectious Disease, Infectious Diseases/Medical Microbiology, Internal Medicine, Neurocritical Care, Non-Thoracic Surgery, Pediatric Critical Care Medicine, Pediatric Infectious Diseases, Surgical Critical Care