Glucose-6-phosphate dehydrogenase is an enzyme found in the cytoplasm of all cells in the body. It is a housekeeping enzyme that prevents cellular damage from reactive oxygen species. It does this by providing substrates to prevent oxidative damage. Erythrocytes are particularly vulnerable to ROS due to their role in oxygen transport and the inability to replace cellular proteins as mature cells. Inherited deficiencies of glucose-6-phosphate Dehydrogenase can result in acute hemolytic anemia during increased reactive oxygen species production. In particular, anti-malarial agents are strongly associated with inducing hemolytic anemia in patients with Glucose-6-phosphate dehydrogenase deficiency. This activity outlines the causes of glucose-6-phosphate dehydrogenase deficiency and highlights the role of the interprofessional team in evaluating and managing patients with this condition.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/22315
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: IPCE Credits: 1.0 hours
AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, General Pediatrics, General Surgery, Hematology, Hematology (Blood, BM), Internal Medicine, Molecular Genetic Pathology, Pediatric Emergency Medicine, Pediatric Hematology-Oncology