Goodpasture syndrome, also known as anti-glomerular basement membrane (anti-GBM) disease, is a rare autoimmune disorder characterized by the production of autoantibodies targeting antigens in the glomerular and alveolar basement membranes. These antibodies, primarily directed against the non-collagenous domain of the α-3 chain of type IV collagen, trigger inflammatory responses involving local complement activation and recruitment of polymorphonuclear leukocytes. Environmental factors, particularly smoking and exposure to hydrocarbon solvents, can precipitate the onset of Goodpasture syndrome in genetically susceptible individuals. Prompt diagnosis and treatment are imperative to prevent irreversible renal damage and pulmonary complications, including life-threatening pulmonary hemorrhage. Early intervention typically involves the initiation of immunosuppressants and plasmapheresis to mitigate autoimmune activity and preserve organ function.In this course, participants delve into the comprehensive evaluation and management of Goodpasture syndrome, gaining insights into early diagnostic markers and evidence-based treatment strategies. They learn to recognize the diverse clinical presentations of the disease and understand the crucial role of immunosuppressive therapy and plasmapheresis in halting disease progression. Moreover, participants explore the significance of collaborative care within an interprofessional team, recognizing how coordination among nephrologists, pulmonologists, pathologists, and other specialists enhances patient outcomes. By fostering interdisciplinary communication and cooperation, clinicians can ensure timely intervention, optimize therapeutic efficacy, and provide holistic support to patients battling Goodpasture syndrome.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/22371
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.5 hours
Nursing: 1.5 hours
Pharmacy: 1.5 hours - MOC Credit Details: ABS - 1.5 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.5 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.5 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.5 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.5 Point; Credit Type(s): Self-Assessment (ABS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Critical Care Medicine, General Surgery, Hospital Medicine, Internal Medicine, Molecular Genetic Pathology, Nephrology, Pulmonary Disease, Pulmonary, Mediastinum, Renal/Medical Renal, Rheumatology