Carbon monoxide (CO) is a toxic gas formed from the incomplete combustion of carbon-containing substances. Common sources are engines, non-electric space heaters, furnaces, and smoke from fires. Poisoning can also occur from inhalation or absorption of methylene chloride (dichloromethane) through the skin. This chemical is commonly used in solvents for paint removal and is metabolized to CO in the liver. CO binds with a higher affinity than oxygen for the hemoglobin molecule in red blood cells, forming carboxyhemoglobin (COHb), which impairs oxygen offloading resulting in hypoxia in body tissues, especially the brain and heart. CO also binds to the cytochrome proteins in mitochondrial impairing cellular respiration. Another mechanism of toxicity is from the precipitation of inflammation in the brain resulting in lipid peroxidation and the delayed neurologic sequelae (DNS). This activity reviews the etiology, presentation, evaluation, and management/prevention of CO toxicity and use of hyperbaric oxygen to treat it and reviews the role of the interprofessional team in evaluating, diagnosing, and managing the condition.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/34483
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Critical Care Medicine, Forensic Pathology, Hospital Medicine, Neurocritical Care, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pulmonary, Mediastinum