Hypocitraturia and Renal Calculi

Hypocitraturia and Renal Calculi

Hypocitraturia is characterized by low citrate levels in the urine and is a significant metabolic abnormality linked to the formation of renal calculi. Citrate—a natural inhibitor of stone formation—binds to calcium in the urine, preventing it from forming crystals that can aggregate into stones. Insufficient citrate levels increase the risk of calcium stone formation, leading to the development of renal calculi. This condition is often associated with various dietary, metabolic, and genetic factors, making its management crucial for preventing recurrent kidney stone episodes and maintaining overall renal health. Hypocitraturia is diagnosed through a 24-hour urine test, often confirmed with a second test. Treatment includes optimizing potassium citrate supplementation and addressing underlying causes when possible. Management involves pharmacological interventions, dietary modifications, and lifestyle changes to increase urinary citrate levels, effectively preventing up to half of symptomatic kidney stones. This activity offers an in-depth exploration of hypocitraturia, its role in the pathogenesis of renal calculi, and contemporary, evidence-based treatment options, including pharmacological interventions, dietary modifications, and lifestyle changes to increase urinary citrate levels and prevent stone formation. In addition, this activity provides healthcare providers with insight into the latest diagnostic techniques, treatment modalities, and preventative strategies for hypocitraturia and kidney stones. This activity also highlights the role of an interprofessional healthcare team in improving patient outcomes through enhanced personalized treatment plans and comprehensive, collaborative care. This activity underscores that an interprofessional healthcare team is essential in optimizing patient outcomes through personalized treatment plans and collaborative care.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/120007
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.5 hours
    Nursing: 1.5 hours
    Pharmacy: 1.5 hours
  • MOC Credit Details: ABS - 1.5 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.5 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABA - 1.5 Point; Credit Type(s): Lifelong Learning (ABA)
    ABIM - 1.5 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.5 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.5 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Bariatric Surgery, Chemical Pathology, Critical Care Medicine, Endocrinology, Diabetes, and Metabolism, Gastroenterology, Geriatric Medicine, Hospital Medicine, Internal Medicine, Medical Toxicology, Molecular Genetic Pathology, Neonatal-Perinatal Medicine, Nephrology, Pediatric Critical Care Medicine, Pediatric Endocrinology, Pediatric Gastroenterology, Pediatric Nephrology, Pediatric Rheumatology, Renal/Medical Renal, Rheumatology, Sports Medicine
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