Hypokalemic periodic paralysis (hypoPP) is a rare channelopathy caused by skeletal muscle ion channel mutations, mainly affecting calcium or sodium channels. Patients with hypoPP experience a sudden onset of generalized or focal flaccid paralysis associated with low blood potassium levels (or hypokalemia), which can last for several hours before resolving spontaneously. Most cases of hypoPP are hereditary or familial. Prompt diagnosis and prophylactic therapy are crucial to managing hypoPP and avoiding associated morbidity. The evaluation for hypoPP includes excluding secondary causes such as hyperthyroidism through thyroid function tests and monitoring for electrocardiogram abnormalities such as prolonged QT interval. Based on patient response, treatment for hypoPP should follow a step-wise escalation, focusing on relieving acute symptoms, managing complications, and preventing future attacks. This underscores the importance of a coordinated approach to improving patient outcomes.This activity provides an overview of the evaluation and treatment of hypoPP, emphasizing the crucial role of the interprofessional healthcare team in both evaluating and treating this condition. An interprofessional healthcare team comprising hospitalists, nurses, dieticians, pharmacists, and geneticists collaborates to provide comprehensive care for managing hypoPP. This approach aims to improve patient outcomes by identifying and avoiding triggers, treating manifestations and complications, and reducing future attacks through monitoring for complications, dietary adjustments, medication management, and genetic testing for at-risk individuals.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/23270
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.5 hours
Nursing: 1.5 hours
Pharmacy: 1.5 hours - MOC Credit Details: ABS - 1.5 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.5 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.5 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.5 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.5 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.5 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Chemical Pathology, Critical Care Medicine, Endocrinology, Diabetes, and Metabolism, Gastroenterology, General Operative Anesthesia, General Pediatrics, General Surgery, Hospital Medicine, Internal Medicine, Medical Toxicology, Molecular Genetic Pathology, Neonatal-Perinatal Medicine, Nephrology, Neuropathology (incl. Neuromuscular), Pediatric Cardiology, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Endocrinology, Pediatric Gastroenterology, Pediatric Nephrology, Pediatric Rheumatology, Rheumatology