Interferons were discovered during investigations into virus interference and have since become essential in treating hepatitis C, cancers, and immune-mediated disorders such as multiple sclerosis. Although interferon therapy is considered effective, it has the potential to induce adverse effects on different systems within the body. A significant adverse effect associated with interferon is retinopathy, identified by flame-shaped retinal hemorrhages, cotton wool spots, and macular edema observed during funduscopic examination. Interferon-induced retinopathy is a potential complication of interferon therapy that may cause temporary and asymptomatic effects. However, due to the risk of vision loss, it is important to take a vigilant approach to prevention and early detection.Determining whether to continue interferon treatment or opt for a dose reduction can be challenging due to the various manifestations that may arise. These manifestations may be caused by the occlusion of retinal capillaries or other ischemic etiologies due to immune complex deposition. Although less likely, severe adverse effects such as retinal artery and vein occlusion and optic neuritis are possible. This activity discusses the etiology, pathophysiology, evaluation, prevention, and management of interferon-induced retinopathy. Healthcare professionals can use this information to screen for retinopathy and make informed decisions on treatment adjustments.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/35602
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Chemical Pathology, Gastroenterology, General Surgery, Hematology, Infectious Disease, Medical Toxicology, Pediatric Gastroenterology, Pediatric Hematology-Oncology, Pediatric Infectious Diseases