In this course, we show you how analysis of the PaO2 in the context of the A-a gradient can help you avoid critical errors in clinical practice. In order to adopt this approach to arterial blood gas (ABG) analysis, certain concepts must first be understood. We begin by explaining how, in response to CO2 produced during metabolism, brainstem centres control the level of alveolar ventilation. We explain how this establishes a strict relationship between the fraction of inspired oxygen (FiO2), the PaO2, the arterial partial pressure of CO2 (PaCO2) and the partial pressure of oxygen in the alveoli (PAO2). We show you how the relationship between these key parameters is described by the alveolar gas equation. We teach you how to use this equation to calculate the PAO2 and the actual A-a gradient present in a patient based on values reported on the ABG. We explain the nature of, and factors contributing to the normal A-a gradient. You will learn how to calculate the predicted appropriate A-a gradient for a patient of a given age on a given level of inspired oxygen. In a series of case studies, we then illustrate how an understanding of the A-a gradient helps us avoid misdiagnosis in practice and allows us to detect problems in patients on oxygen therapy. We also explain two important, commonly misused terms in respiratory medicine, hypoventilation and hyperventilation. We explain the difference between, and the identification of type I and type II respiratory failure.
- Provider:Acadoodle, Ltd.
- Activity Link: https://www.acadoodle.com/courses/16
- Start Date: 2023-07-30 05:00:00
- End Date: 2023-07-30 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 2.0 hours
- Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Competence, Learner Performance
- Provider Ship: Directly Provided
- Registration: Open to all