Krukenberg tumor is a metastatic signet-ring cell adenocarcinoma of the ovary characterized by mucin-rich, signet-ring cells, originating from a gastrointestinal primary in 70% of cases, but also involving the colon, breast, appendix, and biliary tract. The incidence of Krukenberg tumors ranges from 1% to 21%, most common in Asian countries due to the increased prevalence of gastric cancer. Krukenberg tumors are often bilateral and can be solid, cystic, or a combination. Immunohistochemistry stains can help distinguish Krukenberg from primary ovarian cancer. Because Krukenburg tumors present with nonspecific symptoms, the diagnosis is frequently delayed. Krukenberg tumors occur in younger women compared with an ovarian primary. The prognosis is poor, but an overall survival benefit has been shown with palliative surgical resection.This course provides a comprehensive overview of Krukenberg tumors, focusing on epidemiology, clinical presentation, evaluation, and treatment. Participants will gain insights into the diverse origins of these tumors, and emphasis is placed on the challenges in timely diagnosis due to nonspecific symptoms, highlighting the need for vigilant clinical evaluations. Additionally, clinicians will delve into the significance of tumor markers in prognosis and treatment decisions. The course concludes with a nuanced discussion of treatment strategies, encompassing surgery, chemotherapy, targeted immunotherapy, and radiation, acknowledging the absence of standardized guidelines and the importance of an individualized, interdisciplinary approach. The course equips healthcare professionals with the knowledge and tools necessary to navigate the complexities of Krukenberg tumors and optimize patient care outcomes.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/23953
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABTS - 1.0 Point; Credit Type(s): Accredited CME (ABTS)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABTS - 1.0 Point; Credit Type(s): Self-Assessment (ABTS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Complex General Surgical Oncology, Female Reproductive, Gastroenterology, GI (incl. Liver, Pancreas, Bilary), Hospice & Palliative Medicine, Hospice and Palliative Medicine, Hospital Medicine, Internal Medicine, Medical Oncology, Non-Thoracic Surgery