Lafora Disease

Lafora Disease

Lafora disease is a severe, autosomal recessive, progressive myoclonic epilepsy predominantly affecting previously healthy adolescents. Presenting with myoclonus, occipital seizures, and rapid cognitive decline, it progresses rapidly to death within a decade of initial symptom onset. This disease is diagnosed through clinical, electrophysiological, histological, and genetic findings. No curative treatments or preventative interventions are available at present for Lafora disease. Management of Lafora disease focuses on symptomatic relief of seizures and myoclonus, together with palliative, supportive, and rehabilitative measures. By understanding the genetic underpinnings and pathophysiology, healthcare clinicians can better navigate diagnostic challenges and optimize treatment approaches to improve patient outcomes. This activity for healthcare professionals aims to enhance learners’ competence in selecting appropriate diagnostic tests, managing Lafora disease, emphasizing supportive care and symptomatic relief, and fostering effective interprofessional teamwork to improve outcomes.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/24007
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
    Nursing: 1.0 hours
    Pharmacy: 1.0 hours
  • MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
    ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
    ABOHNS - 1.0 Point; Credit Type(s): Self-Assessment (ABOHNS)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Adolescent Medicine, Ambulatory/Outpatient, Critical Care Medicine, General Operative Anesthesia, General Pediatrics, Hospital Medicine, Internal Medicine, Molecular Genetic Pathology, Neurocritical Care, Neuropathology (incl. Neuromuscular), Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Neurology, Sleep Medicine, Sports Medicine
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