Lecithin cholesterol acyltransferase (LCAT) deficiency is a rare autosomal recessive disorder in lipid metabolism, manifesting from early childhood through adulthood. Diminished HDL levels and the accumulation of cholesterol across various tissues characterize this condition. The condition exhibits 2 distinct clinical phenotypes, with complications such as renal dysfunction and corneal opacification contingent upon the specific phenotype. This activity reviews the characteristics of the disease, its underlying pathophysiology, and effective management strategies aimed at curtailing disease progression. Emphasis is placed on the critical need for timely identification of the disease and the proactive management of associated complications. The collaborative efforts of a comprehensive, interprofessional team are pivotal in optimizing patient care.Clinicians participating in this activity can expect to gain a comprehensive understanding of this rare inherited syndrome. The focus includes insights into the pathology involving the partial or complete absence of LCAT enzyme activity, its impact on lipid metabolism, and the resulting abnormal lipid profiles. Participants will acquire knowledge crucial for diagnosing, managing, and mitigating complications related to impaired HDL metabolism.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/148895
- Start Date: 2024-12-01 06:00:00
- End Date: 2024-12-01 06:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABTS - 1.0 Point; Credit Type(s): Accredited CME (ABTS)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABTS - 1.0 Point; Credit Type(s): Self-Assessment (ABTS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Adult Cardiac, Cardiothoracic, Cardiovascular, Cardiovascular Disease, Clinical Pathology, Endocrinology, Diabetes, and Metabolism, Gastroenterology, General Pediatrics, Hematology, Hematology (Blood, BM), Hematopathology (LN, Spleen), Hospital Medicine, Internal Medicine, Pediatric Anesthesia, Pediatric Cardiology, Pediatric Endocrinology, Pediatric Hematology-Oncology, Pediatric Nephrology, Renal/Medical Renal