Leser-Trélat Sign

Leser-Trélat Sign

The Leser-Trélat sign is a rare paraneoplastic cutaneous marker associated with internal malignancies characterized by the abrupt eruption of multiple seborrheic keratoses. The sign of Leser-Trélat is frequently found in connection with colon, breast, or stomach adenocarcinomas but has also been associated with renal, hepatic, and pancreatic malignancies. Although these lesions are typically relatively easy to distinguish from other melanocytic neoplasms, a histopathological examination may be required.This course explores the complexities surrounding this dermatological phenomenon, including the current diagnostic challenges and elusive pathophysiology, exploring the suspected role of cytokines and growth factors in seborrheic keratosis eruption. This activity for healthcare professionals is designed to enhance the learner’s competence in identifying the Leser-Trélat sign, performing the recommended evaluation, and implementing an appropriate interprofessional approach when managing this condition.  

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/24198
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
    Nursing: 1.0 hours
    Pharmacy: 1.0 hours
  • MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABTS - 1.0 Point; Credit Type(s): Accredited CME (ABTS)
    ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
    ABTS - 1.0 Point; Credit Type(s): Self-Assessment (ABTS)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Complex General Surgical Oncology, Dermatopathology, Medical Oncology, Non-Thoracic Surgery, Pediatric Hematology-Oncology
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