Intravenous lipid emulsion (ILE) therapy, also known as lipid resuscitation therapy, is the established standard treatment for local anesthetic systemic toxicity (LAST), including local anesthetic-mediated cardiac arrest. Professional societies such as the American Society of Regional Anesthesia (ASRA) recommend this therapy in the medical field. Although ILE therapy has been experimentally used to rescue lipophilic drug overdoses and toxicities, outcomes vary. ILE therapy is additionally recommended as an adjunct to advanced cardiac life support measures in cases of suspected LAST-induced cardiac arrest.ILE therapy extends beyond LAST to encompass other lipophilic agents, emerging as a potential rescue therapy in emergency rooms and critical care units for various acute toxicities and poisonings. The applicability of this therapy extends across numerous multidisciplinary healthcare professions, including physicians, advanced practice practitioners, nursing staff, and pharmacists, particularly those involved in anesthesiology, emergency medicine, medical toxicology, and critical care departments. Despite its growing recognition, further clinical studies are imperative to clarify its mechanism of action, optimal dosing, and the management of associated complications. This activity provides an overview of the indications and contraindications for ILE therapy—an invaluable agent in managing local anesthetic toxicity. This activity allows participating clinicians to acquire insights into the treatment of patients presenting with local anesthetic toxicity and related conditions via ILE therapy.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/79871
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABOS - 1.0 Point; Credit Type(s): Accredited CME (ABOS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABTS - 1.0 Point; Credit Type(s): Accredited CME (ABTS)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABTS - 1.0 Point; Credit Type(s): Self-Assessment (ABTS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adult Cardiac, Ambulatory/Outpatient, Bariatric Surgery, Cardiac Anesthesia, Cardiothoracic, Cardiovascular, Chemical Pathology, Complex General Surgical Oncology, Congenital Cardiac, Critical Care, Critical Care Medicine, General Operative Anesthesia, General Orthopaedics, General Pediatrics, General Surgery, General Thoracic, Hand Surgery, Hospital Medicine, Internal Medicine, Medical Toxicology, Neurocritical Care, Non-Thoracic Surgery, Pain Medicine, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Surgery, Regional Anesthesia/Acute Pain, Surgical Critical Care, Trauma, Vascular Surgery