Marchiafava-Bignami disease (MBD) is a very rare disorder characterized by demyelination and necrosis of the corpus callosum. The adjacent subcortical white matter may also be involved. This activity describes the pathophysiology, etiology, presentation, and management of MBD. Although clinical features may be quite variable and nonspecific, Marchiafava-Bignami Disease should be considered in patients with chronic alcohol use or malnutrition who present with certain neurological symptoms. These symptoms include dementia, altered mental status, spasticity, dysarthria, ataxia, gait abnormalities, and seizures. Other reported clinical findings include desynchronization of bilateral symmetric movements and unilateral signs of agraphia, apraxia, dyspraxia, and anomia. This activity illustrates the evaluation and management of Marchiafava-Bignami Disease and reviews the role of the interprofessional team in improving care for patients with this condition.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/24741
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Hospital Medicine, Internal Medicine, Neurocritical Care, Neuropathology (incl. Neuromuscular)