Endogenous melatonin is a naturally produced hormone primarily synthesized and secreted in the pineal gland. Melatonin regulates the body’s sleep-wake cycles by interacting with the suprachiasmatic nucleus of the hypothalamus and the retina. The best-known purpose of melatonin is its role in promoting sleep and inhibiting wake-promoting signals through interactions with its MT1 and MT2 receptors. Although melatonin is not officially approved for any indication by the US Food and Drug Administration (FDA) in the United States, exogenously supplied melatonin, which is available as a synthetic dietary supplement, mimics the regulatory functions of endogenous melatonin.The American Academy of Family Physicians (AAFP) recognizes melatonin as the first-line pharmacological therapy for insomnia, emphasizing its crucial role in managing sleep-related concerns. Melatonin is also used for the management of posttraumatic brain injury, jet lag, neurodegenerative disorders, and migraine prophylaxis. This activity explores the safety profile of melatonin supplementation, highlighting its relatively low risk of adverse effects. This activity further elucidates the mechanism of action, pharmacology, adverse event profile, monitoring strategies, and pertinent interactions of melatonin. The interprofessional healthcare team can use melatonin as an adjunct to offer essential insights for collaborative patient care in sleep disorders.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/35398
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.5 hours
Nursing: 1.5 hours
Pharmacy: 1.5 hours - MOC Credit Details: ABS - 1.5 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.5 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.5 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.5 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.5 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.5 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABOHNS - 1.5 Point; Credit Type(s): Self-Assessment (ABOHNS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Chemical Pathology, General Pediatrics, General Surgery, Internal Medicine, Sleep Medicine