Membranous nephropathy (MN) is an immune complex deposition disease. IgG and complements predominantly deposit beneath the podocytes on the sub-epithelial region of glomerular capillaries. Hence, the sub-epithelial deposits are considered to be pathognomonic for MN. Glomerular basement membrane (GBM) injury due to immune deposition causes podocyte structural damage which results in proteinuria. Autoimmune diseases, medications, malignancies, infections, among others, are responsible for generating antibodies that account for about 25% of MN (secondary MN). In about 75 percent of cases of MN, the inciting events for these immune depositions are not known, but specific antigen-antibody complexes have been discovered (primary MN). This activity reviews the causes, evaluation, and management of membranous nephropathy and highlights the role of the interprofessional team in the care of affected patients.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/22285
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Ambulatory/Outpatient, Complex General Surgical Oncology, Critical Care Medicine, General Operative Anesthesia, General Pediatrics, Geriatric Medicine, Hospice & Palliative Medicine, Hospice and Palliative Medicine, Hospital Medicine, Internal Medicine, Medical Oncology, Molecular Genetic Pathology, Nephrology, Neurocritical Care, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Hematology-Oncology, Pediatric Nephrology, Pediatric Rheumatology, Renal/Medical Renal, Rheumatology