Navigating the progressive familial intrahepatic cholestasis (PFIC) landscape: unmet needs and treatment options

Navigating the progressive familial intrahepatic cholestasis (PFIC) landscape: unmet needs and treatment options

In this online, self-learning activity: In this online, self-learning activity: Progressive familial intrahepatic cholestasis (PFIC) is comprised of a group of liver diseases notable for high serum bile salt concentrations and serum bilirubin levels in neonates. It is caused by autosomal recessive mutations in the genes that encode proteins expressed mainly in the bile acid membrane of the hepatocytes and alters hepatocytic bile secretion. PFIC accounts for approximately 9% 13% of cases of neonatal cholestasis liver failure or splenomegaly(2,5,6) and 10% 15% of liver transplantation (LT) cases in childhood. Although its exact prevalence is unknown, it is estimated at 1 2 per 100,000 births.

  • Provider:ScientiaCME
  • Activity Link: https://www.scientiacme.org/cme-531-111-0-1-7-progressive-familial-intrahepatic-cholestasis-pfic-cme
  • Start Date: 2024-07-12 05:00:00
  • End Date: 2024-07-12 05:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
  • MOC Credit Details: ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
  • Commercial Support: Source: Ipsen - Amount: 24950.0 - Is Kind Support: False
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: No, it's free
  • Measured Outcome: Learner Competence, Learner Knowledge, Learner Performance
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Pediatric Gastroenterology
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