Neuroleptics, also known as antipsychotic medications, are used for the treatment and management of symptoms associated with various psychiatric disorders. Neuroleptic medications are categorized into 2 classes—first-generation or “typical” antipsychotics and second-generation or “atypical” antipsychotics. First-generation antipsychotics were initially developed in the 1950s primarily for the treatment of psychosis, such as schizophrenia. In addition to psychotic illnesses, first-generation antipsychotics have been approved by the US Food and Drug Administration (FDA) for treating and managing acute mania, agitation, bipolar disorder, Tourette syndrome, and hyperactivity. Furthermore, second-generation antipsychotics have also been FDA-approved to treat and manage psychosis and treatment-resistant schizophrenia, bipolar disorder, schizoaffective disorder, agitation, and irritability or agitation.Notably, beyond their FDA-approved uses, both first- and second-generation antipsychotics are used in various neuropsychiatric conditions, which are currently considered off-label. These conditions include attention-deficit hyperactivity disorder, behavioral disturbances in dementia, geriatric agitation, depression, eating disorders, personality disorders, insomnia, generalized anxiety disorder, obsessive-compulsive disorder, posttraumatic stress disorder, and substance use and dependence disorders. For many of these conditions, the evidence is inconclusive, and clinicians should use their judgment when considering the prescription of neuroleptics. Neuroleptic medications inhibit dopamine receptors in the nervous system. This activity examines the indications and contraindications of neuroleptics, emphasizing the importance of the interprofessional healthcare team in ensuring safer prescription practices.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/25800
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABOHNS - 1.0 Point; Credit Type(s): Self-Assessment (ABOHNS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, All Practice Areas (e.g. ethics), Ambulatory/Outpatient, Critical Care Medicine, Developmental-Behavioral Pediatrics, General Operative Anesthesia, General Pediatrics, General Surgery, Geriatric Medicine, Hospital Medicine, Internal Medicine, Neurodevelopmental Disabilities, Pain Medicine, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Neurology, Sleep Medicine