Most cases of hydrops fetalis are caused by nonimmune hydrops fetalis (NIHF), characterized by abnormal fluid accumulation in fetal compartments, including the peritoneal cavity, pleura, or generalized skin edema. Unlike immune hydrops fetalis, which primarily results from red blood cell alloimmunization, NIHF arises from various conditions that disrupt fluid regulation in the fetus. These conditions include cardiac abnormalities, infections, metabolic and hematologic disorders, and various genetic abnormalities. The diagnosis of NIHF typically involves prenatal ultrasound, which identifies 2 or more abnormal fluid collections. Management strategies prioritize determining the underlying cause through diagnostic evaluations, such as genetic testing, amniocentesis, and fetal blood sampling. Genetic counseling is crucial, particularly for cases with an inherited recurrence risk. Treatment options for NIHF vary based on the specific etiology and may include intrauterine transfusions for fetal anemia, medications, drainage of pleural effusions, or specialized procedures. The prognosis varies widely depending on the cause, with some cases amenable to fetal therapy, whereas others may have a lethal outcome, requiring consideration of pregnancy termination or comfort care. This activity reviews various treatment options tailored to specific etiologies of NIHF and the implementation of appropriate management strategies, including the use of prenatal ultrasound, genetic testing, amniocentesis, and fetal blood sampling in the diagnostic process. This activity provides clinicians with the knowledge and skills to accurately identify the underlying etiology of NIHF and emphasizes the role of the interprofessional healthcare team in optimizing patient outcomes, thereby promoting a comprehensive approach to managing the condition.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/23081
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.5 hours
Nursing: 1.5 hours
Pharmacy: 1.5 hours - MOC Credit Details: ABS - 1.5 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.5 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.5 Point; Credit Type(s): Lifelong Learning (ABA)
ABS - 1.5 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.5 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Chemical Pathology, Developmental-Behavioral Pediatrics, General Pediatrics, General Surgery, Hospital Medicine, Neonatal-Perinatal Medicine, Neurodevelopmental Disabilities, Pediatric Anesthesia, Pediatric Hematology-Oncology, Pediatric Pathology, Pediatric Pulmonology