Nonketotic hyperglycinemia is a rare, genetic, inborn error of glycine metabolism. Due to a mutation in the glycine cleavage enzyme system, the patient is unable to break down glycine, resulting in its accumulation throughout the body. The buildup of glycine primarily occurs within the spinal cord and brain; thus, the initial clinical manifestations and long-term sequelae from this condition are often neurological. No known interventions are effective in altering the natural history of nonketotic hyperglycinemia, but whatever therapeutic strategies are applied can potentially reduce the comorbidities associated with this condition. It is essential that the clinician recognizes this disease and initiates early evaluation and treatment to attain the best possible outcome. This activity reviews the assessment and management of nonketotic hyperglycinemia and highlights the interprofessional healthcare team’s role in improving care for patients with this condition.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/25960
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: IPCE Credits: 1.0 hours
AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Chemical Pathology, Developmental-Behavioral Pediatrics, Endocrinology, Diabetes, and Metabolism, General Pediatrics, General Surgery, Geriatric Medicine, Hospice & Palliative Medicine, Hospital Medicine, Internal Medicine, Molecular Genetic Pathology, Neonatal-Perinatal Medicine, Neurodevelopmental Disabilities, Pediatric Anesthesia, Pediatric Cardiology, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Gastroenterology, Pediatric Neurology