OnDemand: Physiology of the Weight Reduced State: From Mechanisms to Clinical Application

OnDemand: Physiology of the Weight Reduced State: From Mechanisms to Clinical Application

Long-term weight loss maintenance is seldom achieved by individuals with obesity owing to numerous biological adaptations occurring in the post-weight loss setting, including neuroendocrine-mediated changes in appetite/satiety and reduction of energy expenditure. Following weight loss, peripheral and central mechanisms respond in a way similar to starvation by conveying a sense that energy reserves have dwindled, activating a strong counter-response to increase caloric intake. Moreover, metabolic rate often drops, further compounding the propensity for weight rebound. Evidence suggests these counter-regulatory adaptations may be permanent. Although research is ongoing in this area, early clues have provided valuable insight into clinical management strategies to help patients avoid weight regain. This session will review the current state of knowledge regarding mechanisms of weight regain, identify avenues of further investigation, as well as provide evidence-based clinical strategies to enhance long-term weight loss maintenance in patients with obesity.

  • Provider:Obesity Society, The
  • Activity Link: https://www.obesity.org/meetings-education/on-demand-education/
  • Start Date: 2023-01-04 06:00:00
  • End Date: 2023-01-04 06:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 3.75 hours
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Yes
  • Measured Outcome: Learner Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
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