It was not until 1926 that the use of phenol as a neurolytic agent was described by Doppler et al., followed by a description of intrathecal injection of phenol in 1955. In 1959, Nathan et al. and Kelly et al. described the earliest use of phenol for spasticity and reported relief following intrathecal injections. Phenol is a chemical composite agent that is comprised of carbolic acid, phenic acid, phenylic acid, phenyl hydroxide, hydroxybenzene, and oxybenzone. It denatures protein readily and may cause denervation when injected near neural structures, leading to loss of cellular fatty content, separation of the myelin sheath from the axon, and axonal edema. This activity reviews the role of phenol to denervate nerves, its indications, contraindications and highlights the role of the interprofessional team in the management of patients with chronic pain.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/27113
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABOS - 1.0 Point; Credit Type(s): Accredited CME (ABOS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABTS - 1.0 Point; Credit Type(s): Accredited CME (ABTS)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABTS - 1.0 Point; Credit Type(s): Self-Assessment (ABTS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: All Practice Areas (e.g. ethics), General Surgery, Non-Thoracic Surgery, Pain Medicine, Regional Anesthesia/Acute Pain, Surgery of the Spine