Phenylephrine primarily acts as an alpha-1 adrenergic receptor agonist and exhibits minimal to no beta-adrenergic activity. Consequently, the medication is an optimal choice for raising mean arterial pressure by inducing vasoconstriction in both veins and arteries and enhancing cardiac preload without exerting significant effects on cardiac myocytes. The US Food and Drug Administration (FDA) has approved intravenous phenylephrine hydrochloride to elevate blood pressure in adults experiencing clinically significant hypotension, primarily attributed to vasodilation, in situations such as septic shock or anesthesia. Phenylephrine HCL is also an over-the-counter (OTC) medication in ophthalmic formulations to facilitate mydriasis and vasoconstriction of conjunctival blood vessels. Furthermore, this medication is administered intranasally to treat uncomplicated nasal congestion and is an OTC additive to topical hemorrhoid medications.This activity provides a comprehensive overview of the indications, mechanism of action, administration methods, adverse event profile, contraindications, monitoring, and toxicity of phenylephrine relevant to the interprofessional healthcare team to effectively guide patient therapy in the treatment of diverse conditions for which phenylephrine is indicated.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/27119
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: IPCE Credits: 1.0 hours
AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABTS - 1.0 Point; Credit Type(s): Accredited CME (ABTS)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABOHNS - 1.0 Point; Credit Type(s): Self-Assessment (ABOHNS)
ABTS - 1.0 Point; Credit Type(s): Self-Assessment (ABTS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: All Practice Areas (e.g. ethics), Ambulatory/Outpatient, Bariatric Surgery, Cardiac Anesthesia, Complex General Surgical Oncology, Critical Care, Critical Care Medicine, Gastroenterology, General Operative Anesthesia, General Otolaryngology, General Pediatrics, General Surgery, Internal Medicine, Medical Toxicology, Neuro Anesthesia, Neurocritical Care, Obstetric Anesthesia, Pain Medicine, Pediatric Anesthesia, Pediatric Cardiology, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Gastroenterology, Pediatric Surgery, Regional Anesthesia/Acute Pain, Surgical Critical Care, Thoracic Anesthesia, Vascular Surgery