Pigment Dispersion Syndrome

Pigment Dispersion Syndrome

Pigment dispersion syndrome (PDS) is a common type of open-angle glaucoma which is relatively underdiagnosed. It is characterized by the spontaneous dispersion of pigment granules from the pigment epithelium of the iris, which gets deposited in the anterior segment. It is a bilateral condition that is more commonly encountered in myopic young males. Secondary pigment dispersion can be seen after ocular trauma, tumors of the iris, and rubbing the IOL against the surface of the iris. Secondary pigmentary glaucoma (PG) is also common and can coexist. The patients with PDS are usually asymptomatic, and occasionally patients may present with pain, redness, extreme photophobia, and reduced visual acuity. Approximately 15% of patients with PDS will convert to PG after 15 years. The classical clinical features of PDS include corneal edema, Krukenberg spindles, pigments in the anterior chamber, concave iris configuration, iris transillumination defects, pigments on the anterior lens surface with Scheie stripe, and Zentmayer ring of pigments. The posterior segment features can be myopic lattice degeneration, peripheral retinal pigmentation, occasionally retinal detachment, and glaucomatous cupping, which depends on the stage of the disease. The essential diagnostic tools for PDS are intraocular pressure assessment, gonioscopy, visual field, anterior segment optical coherence tomography (OCT), posterior segment OCT, posterior segment OCT angiography, and ultrasound biomicroscopy. The recommended management options are lifestyle modifications, antiglaucoma medications, laser iridotomy, iridoplasty, and filtration surgery. This activity highlights the role of the interprofessional team in the evaluation and management of patients with pigment dispersion syndrome.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/143509
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
    Nursing: 1.0 hours
    Pharmacy: 1.0 hours
  • MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: All Practice Areas (e.g. ethics), General Surgery
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