Plasmablastic lymphoma (PBL) is an uncommon but aggressive subtype of diffuse, large B-cell lymphoma classically seen in association with HIV infection. Despite significant advances in the field of lymphomas since this subtype was first described in a case series by Delecluse et al in 1997, PBL continues to pose challenges with diagnosis and management. The primary organs involved are the gastrointestinal system, lymph nodes, oral mucosa, and sometimes the skin. Patients usually present with extranodal masses involving the oral cavity or the gastrointestinal tract. Nodal disease without extranodal involvement is rare.PBL is diagnosed primarily through histologic evaluation with or without genetics and immunophenotyping. However, diagnosing PBL is difficult due to overlapping features with plasmablastic myeloma and other high-grade lymphomas with plasmablastic morphology. Chemotherapy remains the cornerstone of the management of PBL and requires a multidisciplinary approach incorporating medical oncology and infectious disease experts. At the same time, PBL has an aggressive and relapsing course, which results in poor outcomes despite the institution of multi-drug intensive chemotherapy regimens and autologous stem cell transplantation. Optimal treatment strategies remain unclear partly because of the relative rarity of this disease. This activity for healthcare professionals is designed to enhance the learner’s competence when managing plasmablastic lymphoma, equipping them with updated knowledge, skills, and strategies for timely identification, effective interventions, and improved care coordination, leading to better patient outcomes and reduced morbidity.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/41880
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: IPCE Credits: 1.0 hours
AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABOS - 1.0 Point; Credit Type(s): Accredited CME (ABOS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABOHNS - 1.0 Point; Credit Type(s): Self-Assessment (ABOHNS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Ambulatory/Outpatient, Critical Care Medicine, Gastroenterology, General Operative Anesthesia, General Orthopaedics, General Otolaryngology, General Pediatrics, Geriatric Medicine, GI (incl. Liver, Pancreas, Bilary), Head & Neck/Oral, Hematology, Hematology (Blood, BM), Hospice & Palliative Medicine, Hospice and Palliative Medicine, Hospital Medicine, Internal Medicine, Medical Oncology, Musculoskeletal Oncology, Pediatric Gastroenterology, Pediatric Hematology-Oncology