Propofol is a phenol derivative administered intravenously that is commonly used for sedation and in general anesthesia. The most common formulation of propofol is a lipophilic emulsion, which allows for rapid distribution into the tissues, including across the blood-brain barrier. It is commonly used for sedation in the intensive care unit (ICU) because it has a short duration of action and rapid clearance. It has dose-dependent effects, leading to higher blood pressure and heart rate changes at higher doses. The initial administration can cause pain at the injection site. Though propofol has a generally favorable profile as a sedative, administration of toxic doses can have harmful effects. Propofol infusion syndrome (PRIS) results from propofol toxicity. This activity reviews the presentation, evaluation, and management of propofol toxicity and stresses the role of an interprofessional team approach in caring for affected patients.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/301
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABOHNS - 1.0 Point; Credit Type(s): Self-Assessment (ABOHNS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Ambulatory/Outpatient, Bariatric Surgery, Chemical Pathology, Clinical Cardiac Electrophysiology, Complex General Surgical Oncology, Critical Care Medicine, Forensic Pathology, General Operative Anesthesia, General Otolaryngology, General Surgery, Hand Surgery, Hospital Medicine, Interventional Cardiology, Medical Toxicology, Neurocritical Care, Pediatric Cardiology, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Pulmonology, Pediatric Surgery, Surgical Critical Care, Vascular Surgery