Neuromuscular junction (NMJ) disorders result from impaired transmission of neural signals across the nerve-muscle interface, resulting in debilitating weakness of the affected muscles. Neuromuscular junction transmission disorders have various causes and manifestations and include myasthenia gravis, Lambert-Eaton syndrome, and botulism. Myasthenia gravis is an acquired autoimmune disorder and is the most commonly encountered NMJ disorder in clinical practice. Diagnosing NMJ disorders requires careful history taking, physical examination, and standard electrodiagnostic testing. Repetitive nerve stimulation (RNS) is an electrophysiological study that evaluates the integrity of the NMJ. RNS can confirm the diagnosis of an NMJ disorder and pinpoint which element of signal transmission is impaired. This activity reviews the relevant anatomy, physiology, pathophysiology, indications, contraindications, and technique for performing RNS and highlights the role of the interprofessional team in performing a comprehensive evaluation of patients with NMJ disorders.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/143432
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: All Practice Areas (e.g. ethics), General Pediatrics, General Surgery, Internal Medicine, Pediatric Neurology