Romosozumab is a humanized monoclonal antibody sclerostin inhibitor that is United States Food and Drug Administration (FDA)-approved to treat osteoporosis in postmenopausal women who are at an increased risk of fracture. This anabolic medication stimulates bone formation while suppressing bone resorption. This activity focuses on the indications, administration, and contraindications of romosozumab and the mechanism of action, FDA-issued box warnings, adverse drug reactions, pharmacokinetics, and recommended clinical monitoring. A thorough understanding of romosozumab’s pharmacology enables healthcare professionals to personalize treatment plans based on individual patient needs. This knowledge allows informed decision-making when prescribing romosozumab and optimizing dosage regimens while minimizing adverse reactions. This discussion also emphasizes the essential role of the interprofessional healthcare team in managing romosozumab therapy for osteoporosis.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/145296
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABOS - 1.0 Point; Credit Type(s): Accredited CME (ABOS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adult Reconstruction, All Practice Areas (e.g. ethics), Endocrinology, Diabetes, and Metabolism, General Orthopaedics, General Surgery, Geriatric Medicine, Internal Medicine, Orthopaedic Trauma, Rheumatology, Sports Medicine, Surgery of the Hand, Surgery of the Spine